Date of Award
8-11-2018
Document Type
Thesis
Degree Name
Chemistry, MS
First Advisor
John Hershberger
Committee Members
Allyn Ontko; Hashim Ali
Call Number
LD 251 .A566t 2018 C65
Abstract
The Biginelli reaction has been a distinguished reaction for many years. Their products, the Dihydropyrimidones have been shown to contain a vast array of bioactivity especially when they contain other known bioactive functional groups. Here in we discuss different pathways that these DHPM products can be taken down to combine them with other such bioactive functional groups. We explored the addition of alkene and aldehyde groups to the Biginelli compounds in hopes of synthesizing potential drug candidates. We believe the synthesis of the aldehyde group on the DHPM compounds is a gateway to obtaining the hybrid drug activity we so hope to find.
Rights Management
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Collins, Michelle Sarah, "Synthesis Of Modified Biginelli Compounds" (2018). Student Theses and Dissertations. 501.
https://arch.astate.edu/all-etd/501
