Date of Award

6-12-2025

Document Type

Thesis

Degree Name

Mathematics, MS

First Advisor

Hao Yang Teng

Committee Members

Jason Causey; Sudeepa Bhattacharyya; Xiao Huang

Call Number

ISBN 9798280760516

Abstract

Colorectal cancer (CRC) is one of the most common and preventable cancers, yet significant disparities in screening, incidence, and late-stage diagnosis persist across different geographic and socioeconomic contexts. This thesis presents a spatial modeling framework for identifying multidimensional risk factors associated with CRC outcomes across various geographic scales. Using county- and census-tract-level data from national and state sources, the study integrates demographic, socioeconomic, environmental, built environment, and behavioral predictors to analyze geographic variability in CRC risk factors. Advanced spatial modeling techniques, including Geographically Weighted Regression (GWR) and Geographically Weighted Random Forest (GW-RF), are employed to capture spatial heterogeneity in these relationships. The results highlight distinct geographic clusters of high and low CRC burden and underscore the importance of incorporating spatially explicit methods to identify localized risk factors. Findings from this study can inform targeted public health interventions and policy strategies aimed at reducing disparities and improving CRC prevention and early detection efforts.

Rights Management

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Included in

Mathematics Commons

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